XB-FEAT-12564498: Difference between revisions
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=''col11a2 | =''col11a2''= | ||
This is the community wiki page for the gene ''col11a2 | This is the community wiki page for the gene ''col11a2''' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | =nomenclature changes= | ||
Revision as of 11:09, 1 May 2023
col11a2
This is the community wiki page for the gene col11a2' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
01MAY2023
Xenopus gene symbol was changed from col11a2 to col11a2.2
Xenopus gene name was changed from collagen type XI alpha 2 chain to collagen type XI alpha 2 chain gene 2
orthology and synteny
1MAY2023
2 different 'collagen type XI alpha 2 chain' genes are annotated on Chromosome 8 in the v10 X. tropicalis genome:
1) GeneID:100488265 (not represented on a Xenbase genepage)
2) GeneID:448277 on this gene page XB-GENEPAGE-12564498
Synteny supports the X. tropicalis GeneID:448277 as the true ortholog of human COL11A2, as it is flanked by a MHC-gene and rxrb:
Synteny:
HUMAN Chr6: LOC(UNCH)< MHC/HLA-DPA3> HCG24> COL11A2< RXRB< SLC39A7>
X.tropChr8 GeneID:100488265: kifcl< mgc147402< rxrb> col11a2> mhc-dab< loc100487257<
X.tropChr8 GeneID:448277: loc(ficolin1b) loc(ficolin1b-like) col11a2> Xb5814630 loc(inkt) loc(nnmt)
This indicates the need for nomenclature change for X.trop GeneID:448277 from col11a2 to col11a2.2, and a new gene page (requested) for the true col11a2!