XB-FEAT-876668

col11a2

This is the community wiki page for the gene col11a2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

04/22/ 2016

Human name has changed for Entrez Gene: 394214. From collagen, type XI, alpha 2 pseudogene 1 to collagen type XI alpha 2 pseudogene 1

3OCT2023

Renamed gene, changing from col11a2p1 to col11a2, removing ‘p1’ suffix as these are protein coding genes in Xenopus.

Humans have a true pc gene and an adjacent pseudogene on Chr6, flanked by BRD2 and RXRB. Xenopus tropicalis and X.laevis.S both have orthologous genes.

Also, removed the human COL11A2P1 as ortholog from this gene page (done)

Orthology and Synteny

Synteny shows that these genes are the true orthologs of human COL11A2, and therefore orthologs were moved from XB-GENEPAGE-12564498 to XB-GENEPAGE-876668

Xtr.chr8: /// syngap1.L< LOC100486535(unch) cuta.L> phf1 < slc39a7 < hsd17b8> ring1>//// rxrb> col11a2*(was col11a2p1- not a pseudogene)> mhc2-dcb< post12< tap1< tap2> (*needed model updates on gene page)

Xla.Chr8L: syngap1.L< cuta.L> phf1.L< slc39a7.L< ring1.L> ///LOC100137644(unch|?hmga2)< rxrb.L> mhc-dab.L< mhc-daa.L> LOC108719087(p2rx7-like)< mhc2-dcb.L(eladab-a)< mhc2-dca.L> mhc2-dbb.L< LOC121397044(unch|)< LOC121397045<. mhc2-dba

Not present in Xlaevis L sub genome!

Xla.Chr8S: slc39a7.S < hsd17b8> ring1> rps18.S> wdr46.2> pfdn6.S> tapbp.S< zbtb22.S< LOC100126628(unch|?hmga2)< rxrb.S> LOC108700220(col11a2.S)> brd.S< mhc2-dma.S

Human: chr6: BRD2> HLA-DOA< HLA-DPA1< HLA-DPB1> HLA-DPA2< COL11A2P1< COL11A2< RXRB< SLC39A7> RING1>