XB-FEAT-5810263: Difference between revisions
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Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, May 2025] | Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, May 2025] | ||
= nomenclature changes= | = nomenclature changes= | ||
At some point in past (i.e., prior to 12/01/2018) gene name changed for ''tpx2'' from ''Xklp2, Xenopus kinesin-like protein 2'' to 'TPX2, microtubule nucleation factor ' | |||
The gene symbol changed from ''Xklp2'' to ''tpx2'' | |||
Note that species' names (''Xenopus, Drosophila'' etc) have been removed from nearly all human gene names during period 2010-2020, following HGNC nomenclature guidelines. | |||
Note that species names (Xenopus, Drosophila etc) have been removed from nearly all gene names during period 2010-2020. | |||
Revision as of 09:52, 10 May 2025
tpx2
This is the community wiki page for the gene tpx2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
summary from NCBI for Human gene TPX2
Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, May 2025]
nomenclature changes
At some point in past (i.e., prior to 12/01/2018) gene name changed for tpx2 from Xklp2, Xenopus kinesin-like protein 2 to 'TPX2, microtubule nucleation factor '
The gene symbol changed from Xklp2 to tpx2
Note that species' names (Xenopus, Drosophila etc) have been removed from nearly all human gene names during period 2010-2020, following HGNC nomenclature guidelines.