XB-FEAT-29089782: Difference between revisions
Created page with "=''or6n3''= =nomenclature updates= 14MAY2026 ''Xenopus'' gene name was changed from ''or6n3, olfactory receptor family 6 subfamily N member 3'' to ''or6n2, olfactory receptor family 6 subfamily N member 2'' to match the human ortholog as identified by NCBI. Note tha Olfactory Receptors are short 1 exon genes that evolve quickly, and generally are impossible to classify by sequence similarity or synteny. ''Xenopus'' ORs have a unique naming system, however, ''or6n3'' s..." |
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=summary from NCBI for human OR6N2= | |||
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008] | |||
Revision as of 13:22, 14 May 2026
or6n3
nomenclature updates
14MAY2026
Xenopus gene name was changed from or6n3, olfactory receptor family 6 subfamily N member 3 to or6n2, olfactory receptor family 6 subfamily N member 2 to match the human ortholog as identified by NCBI.
Note tha Olfactory Receptors are short 1 exon genes that evolve quickly, and generally are impossible to classify by sequence similarity or synteny. Xenopus ORs have a unique naming system, however, or6n3 seems very simialr to the Human OR6N3, so we are happy to give it the same symbol, although it is probably NOT a true ortholog (ie with shared inherited ancestry).
CJZ
summary from NCBI for human OR6N2
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]