XB-FEAT-1014089: Difference between revisions
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=bace2= | =bace2= | ||
This is the community wiki page for the gene ''bace2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''bace2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=summary from NCBI= | |||
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] | |||
=nomenclature changes= | |||
05.14.2018 | |||
Human name has changed for Entrez Gene: 25825. From beta-site APP-cleaving enzyme 2 to beta-secretase 2 | |||
Latest revision as of 13:18, 15 May 2018
bace2
This is the community wiki page for the gene bace2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
summary from NCBI
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
nomenclature changes
05.14.2018 Human name has changed for Entrez Gene: 25825. From beta-site APP-cleaving enzyme 2 to beta-secretase 2