XB-FEAT-980520: Difference between revisions
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=pros1= | =pros1= | ||
This is the community wiki page for the gene ''pros1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''pros1'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
= nomenclature changes= | |||
08/15/2017 | |||
Human name has changed for Entrez Gene: 5627. From protein S (alpha) to protein S | |||
=summary from NCBI= | |||
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015] | |||
Latest revision as of 07:48, 15 August 2017
pros1
This is the community wiki page for the gene pros1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
08/15/2017 Human name has changed for Entrez Gene: 5627. From protein S (alpha) to protein S
summary from NCBI
This gene encodes a vitamin K-dependent plasma protein that functions as a cofactor for the anticoagulant protease, activated protein C (APC) to inhibit blood coagulation. It is found in plasma in both a free, functionally active form and also in an inactive form complexed with C4b-binding protein. Mutations in this gene result in autosomal dominant hereditary thrombophilia. An inactive pseudogene of this locus is located at an adjacent region on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein. [provided by RefSeq, Oct 2015]