XB-FEAT-854069: Difference between revisions
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=kirrel2= | =kirrel2= | ||
This is the community wiki page for the gene ''kirrel2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''kirrel2'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
06/12/2017 | |||
Human name has changed for Entrez Gene: 84063. From kin of IRRE like 2 (Drosophila) to kirre like nephrin family adhesion molecule 2 | |||
=summary from NCBI= | |||
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016] | |||
Latest revision as of 14:44, 15 June 2017
kirrel2
This is the community wiki page for the gene kirrel2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
06/12/2017 Human name has changed for Entrez Gene: 84063. From kin of IRRE like 2 (Drosophila) to kirre like nephrin family adhesion molecule 2
summary from NCBI
This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter. [provided by RefSeq, Jul 2016]