XB-FEAT-965579: Difference between revisions
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= | =tlcd3a= | ||
This is the community wiki page for the gene '' | This is the community wiki page for the gene ''tlcd3a'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase. | ||
=nomenclature changes= | |||
05.13.19 | |||
Human symbol has changed for genepage ID: 965579 From fam57a to tlcd3a | |||
Human symbol has changed for Entrez Gene: 79850. From FAM57A to TLCD3A | |||
Human name has changed for Entrez Gene: 79850. From family with sequence similarity 57 member A to TLC domain containing 3A | |||
=Summary from NCBI for human TLCD3A= | |||
The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] | |||
Latest revision as of 12:01, 21 May 2019
tlcd3a
This is the community wiki page for the gene tlcd3a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.
nomenclature changes
05.13.19
Human symbol has changed for genepage ID: 965579 From fam57a to tlcd3a
Human symbol has changed for Entrez Gene: 79850. From FAM57A to TLCD3A
Human name has changed for Entrez Gene: 79850. From family with sequence similarity 57 member A to TLC domain containing 3A
Summary from NCBI for human TLCD3A
The protein encoded by this gene is a membrane-associated protein that promotes lung carcinogenesis. The encoded protein may be involved in amino acid transport and glutathione metabolism since it can interact with a solute carrier family member (SLC3A2) and an isoform of gamma-glutamyltranspeptidase-like 3. An alternatively spliced variant encoding a protein that lacks a 32 aa internal segment showed the opposite effect, inhibiting lung cancer cell growth. Knockdown of this gene also inhibited lung carcinogenesis and tumor cell growth. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015]