AZD1480: Difference between revisions
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==Suppliers== | ==Suppliers== | ||
*[https://pubchem.ncbi.nlm.nih.gov/compound/16659841 PubChem] | |||
*[http://www.selleckchem.com/products/azd1480.html Selleck Chemicals] | *[http://www.selleckchem.com/products/azd1480.html Selleck Chemicals] | ||
*[http://www.scbt.com/datasheet-364735-azd1480.html Santa Cruz ] | *[http://www.scbt.com/datasheet-364735-azd1480.html Santa Cruz ] |
Latest revision as of 12:28, 2 June 2015
Description
Inhibits the Jak Stat pathway. AZD1480 is a novel ATP-competitive JAK2 inhibitor with IC50 of 0.26 nM in a cell-free assay, selectivity against JAK3 and Tyk2, and to a smaller extent against JAK1. Phase 1.