SB431542: Difference between revisions

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==References==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=371 Ho et al., 2006]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=371 Ho et al., 2006]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=49634 Chiu 2014]
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]
*[https://pubchem.ncbi.nlm.nih.gov/ Pubchem]



Revision as of 07:53, 8 March 2016

Description

"Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells."

  • -Tocris Product Description
SB-431542 structure, photo from Sigma-Aldrich

Genes Affected

Suppliers

Usage Notes

References

>23 Xenbase articles contain a reference to SB-431542 according to textpresso