SB431542: Difference between revisions
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*[https://pubchem.ncbi.nlm.nih.gov/compound/4521392 NCBI PubChem CID:4521392] | *[https://pubchem.ncbi.nlm.nih.gov/compound/4521392 NCBI PubChem CID:4521392] | ||
> | > 40 Xenbase articles contain a reference to SB431542 according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso] | ||
* | * | ||
*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | *[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]] | ||
Revision as of 12:19, 9 April 2018
Description
"Potent and selective inhibitor of the transforming growth factor-β (TGF-β) type I receptor activin receptor-like kinase ALK5 (IC50 = 94 nM), and its relatives ALK4 and ALK7. Suppresses TGF-β-induced proliferation of human osteosarcoma cells. Stimulates proliferation, differentiation and sheet formation of ESC-derived endothelial cells."
- -Tocris Product Description
Genes Affected
Suppliers
Usage Notes
References
> 40 Xenbase articles contain a reference to SB431542 according to textpresso