Cyclosporin A: Difference between revisions
Jump to navigation
Jump to search
imported>Kevin No edit summary |
imported>Kevin No edit summary |
||
| Line 8: | Line 8: | ||
==Genes Affected== | ==Genes Affected== | ||
*[http://www.xenbase.org/gene/showgene.do?method=display&geneId=952298 ppp3ca (Calcineurin)] | |||
==Suppliers== | ==Suppliers== | ||
*[http://www.emdmillipore.com/US/en/product/Cyclosporin-A%2C-Tolypocladium-inflatum---CAS-59865-13-3---Calbiochem,EMD_BIO-239835?RedirectedFrom=http://www.emdmillipore.com/products/EMD_BIO-239835 Calbiochem] | *[http://www.emdmillipore.com/US/en/product/Cyclosporin-A%2C-Tolypocladium-inflatum---CAS-59865-13-3---Calbiochem,EMD_BIO-239835?RedirectedFrom=http://www.emdmillipore.com/products/EMD_BIO-239835 Calbiochem] | ||
Revision as of 07:10, 13 October 2015
Description
"Cyclic oligopeptide with immunosuppressant properties. Induces apoptosis in rat thymocytes and in the murine B cell lymphoma cell line, WEH1-231. However, prevents anti-IgM and ionomycin-induced apoptosis in BLB cell lines. The complex of cyclosporin A with cyclophilin inhibits protein phosphatase 2B with nanomolar affinity. Inhibits nitric oxide synthesis induced by interleukin-1α, lipopolysaccharides, and TNF-α. Induces cardiomyocytes from embryonic stem cells."
- -Calbiochem Product Description
Synonym CsA
Genes Affected
Suppliers
Usage Notes
References
>161 Xenbase articles contain a reference to Cyclosporin A according to textpresso