Rapamycin: Difference between revisions

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imported>Kevin
Created page with "http://www.xenbase.org/literature/article.do?method=display&articleId=11687 Synonym Rap Calbiochem"
 
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http://www.xenbase.org/literature/article.do?method=display&articleId=11687
==Description==
Synonym  Rap
"Rapamycin is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties."
 
*-Pubchem Description
[[File:rapamycin.png|frame|right|rapamycin structure, photo from PubChem]]
 
==Genes Affected==


Synonym  Rap
==Suppliers==
Calbiochem
*[http://www.emdmillipore.com/US/en/product/Rapamycin---CAS-53123-88-9---Calbiochem,EMD_BIO-553210 Calbiochem]
 
==Usage Notes==
 
==References==
*[https://pubchem.ncbi.nlm.nih.gov/compound/5284616 Pubchem]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=11687 Lautermilch et al., 2000]
 
>172 Xenbase articles contain a reference to rapamycin according to [http://www.xenbase.org/cgi-bin/textpresso/xenopus/search textpresso]
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*[[Small Molecules for Xenopus Research|Back To Small Molecules Home Page]]

Latest revision as of 08:08, 13 October 2015

Description

Synonym Rap "Rapamycin is a macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties."

  • -Pubchem Description
rapamycin structure, photo from PubChem

Genes Affected

Suppliers

Usage Notes

References

>172 Xenbase articles contain a reference to rapamycin according to textpresso