BMS-453: Difference between revisions

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==Chemical Name==
==Chemical Name==
4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid
4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid
==Pubchem ID==
CID:9875424
==Suppliers==
==Suppliers==
*[https://www.tocris.com/dispprod.php?ItemId=222005#.V2xIRfkrKM8 Tocris]
*[https://www.tocris.com/dispprod.php?ItemId=222005#.V2xIRfkrKM8 Tocris]
==References==
==References==
*[http://www.xenbase.org/literature/article.do?method=display&articleId=51800| ''Using frogs faces to dissect the mechanisms underlying human orofacial defects''. Dickinson AJ. Semin Cell Dev Biol. March 1, 2016; 51 54-63.]
*[http://www.xenbase.org/literature/article.do?method=display&articleId=51800| ''Using frogs faces to dissect the mechanisms underlying human orofacial defects''. Dickinson AJ. Semin Cell Dev Biol. March 1, 2016; 51 54-63.]

Revision as of 13:53, 23 June 2016

Description

Synthetic retinoid. Retinoic acid receptor β (RARβ) agonist in vivo; RARα and RARγ antagonist in vitro. Inhibits breast cell proliferation by inducing active transforming growth factor β (TGFβ) and causes G1 arrest.

Bms 453 structure, photo from Tocris

Alternative Name

BMS 189453

Chemical Name

4-[(1E)-2-(5,6-Dihydro-5,5-dimethyl-8-phenyl-2-naphthalenyl)ethenyl]-benzoic acid

Pubchem ID

CID:9875424

Suppliers

References