XB-FEAT-6071789: Difference between revisions

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04APRIL2023
04APRIL2023


Despite suggestions from DIOPT Analysis, this gene is not orthologous with kdrl. In Xtrop and  in Zebrafish, ''kdrl'' is adjacent to ''chic1'' and ''cdx4''.  
Despite suggestions from DIOPT Analysis, this gene is not orthologous with human KDRL.  


In Xtrop and  in Zebrafish, ''kdrl'' is adjacent to ''chic1'' and ''cdx4'', whereas flt1 is flanked by ''slc46a3'' and ''pan3''


There does not appear to be an orthologous human gene for ''flt1''
 
There does '''not''' appear to be an orthologous human gene for ''flt1'' ( I missing in human and other mammals)
 
=synteny=


Synteny across ''Xenopus'' is highly conserved:
Synteny across ''Xenopus'' is highly conserved:


''Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] flt1> pan3< flt3>''
''Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] '''flt1'''> pan3< flt3>''


''Xla.L : mtus2.L >  slc46a3.L flt1.L> pan3.L< flt3.L>''
''Xla.L : mtus2.L >  slc46a3.L '''flt1.L>''' pan3.L< flt3.L>''


''Xla.S : mtus2.S >  slc46a3.S flt1.S> pan3.S< flt3.S>''
''Xla.S : mtus2.S >  slc46a3.S '''flt1.S>''' pan3.S< flt3.S>''

Revision as of 08:28, 25 April 2023

flt1

This is the community wiki page for the gene flt1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

orthology and synteny notes

04APRIL2023

Despite suggestions from DIOPT Analysis, this gene is not orthologous with human KDRL.

In Xtrop and in Zebrafish, kdrl is adjacent to chic1 and cdx4, whereas flt1 is flanked by slc46a3 and pan3


There does not appear to be an orthologous human gene for flt1 ( I missing in human and other mammals)

synteny

Synteny across Xenopus is highly conserved:

Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] flt1> pan3< flt3>

Xla.L : mtus2.L > slc46a3.L flt1.L> pan3.L< flt3.L>

Xla.S : mtus2.S > slc46a3.S flt1.S> pan3.S< flt3.S>