XB-FEAT-6071789: Difference between revisions
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Whereas ''flt1'' is flanked by ''slc46a3'' and ''pan3'' in all mammals, fish and frogs | Whereas ''flt1'' is flanked by ''slc46a3'' and ''pan3'' in all mammals, fish and frogs, and synteny across ''Xenopus'' is highly conserved for ''flt1'': | ||
''Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] '''flt1'''> pan3< flt3>'' | ''Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] '''flt1'''> pan3< flt3>'' | ||
Revision as of 08:55, 25 April 2023
flt1
This is the community wiki page for the gene flt1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
orthology and synteny notes for kdrl v. flt1
24APRIL2023
Despite suggestions from DIOPT Analysis, Xenopus kdrl genes are not orthologous with human ITL1. Note: There does not appear to be an orthologous mammalian gene for kdrl, and it only annotated in fishes and frogs. (ie it is missing in human and other mammals)
In Xtrop and in Zebrafish, kdrl is adjacent to chic1 and cdx4:
Xtr.chr8: amer1> ... arhgef9> ... kdrl> ... loc#> ... cdx4> ... chic1>
Xla.chr8L: amer1.L> ... arhgef9.L> ... kdrl.L> ... cdx4.L> ...
Dre.chr14: gdpd2< ... dlg3< ...tex11> ... kdrl> ... cdx4> ... chic1>
Whereas flt1 is flanked by slc46a3 and pan3 in all mammals, fish and frogs, and synteny across Xenopus is highly conserved for flt1:
Xtrop: mtus2 > [LOC#9015(p) LOC#9139(unch) LOC(unch) LOC#9957] flt1> pan3< flt3>
Xla.L : mtus2.L > slc46a3.L flt1.L> pan3.L< flt3.L>
Xla.S : mtus2.S > slc46a3.S flt1.S> pan3.S< flt3.S>
Human CHR13: SLC46A3 ... FLT1...PAN3 ...FLT3
Dre.chr: slc46a3 ... flt1 ... pan3 .. flt3