XB-FEAT-5961451: Difference between revisions
imported>Xenbase |
|||
| Line 1: | Line 1: | ||
=c6 | =''c6''= | ||
This is the community wiki page for the gene ''c6'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | This is the community wiki page for the gene ''c6'' please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase | ||
=nomenclature changes= | =nomenclature changes= | ||
02.25.20 | 02.25.20 | ||
Revision as of 12:04, 23 September 2024
c6
This is the community wiki page for the gene c6 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase
nomenclature changes
02.25.20 name changed from 'complement component 6, gene 1' to 'complement C6, gene 1' to follow human nomenclature conventions.
Note that Xenopus laevis has a gene duplication of c6 genes, and both are side-by-side on Chr1, and both are orthologous to human C6.
Summary for human C6 from NCBI
This gene encodes a component of the complement cascade. The encoded protein is part of the membrane attack complex that can be incorporated into the cell membrane and cause cell lysis. Mutations in this gene are associated with complement component-6 deficiency. Transcript variants encoding the same protein have been described.[provided by RefSeq, Nov 2012]