XB-FEAT-855943: Difference between revisions

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On 7/3/2019, this gene was changed from ''h2afx'' to ''h2afxl'' to designate that it is a like gene.
On 7/3/2019, this gene was changed from ''h2afx'' to ''h2afxl'' to designate that it is a like gene.
As Xenopus follows human nomenclature, XB kept the 'like' designation,  so new name is H2A.X variant histone-like, and new symbol for ''Xenopus'' gene is ''h2axl''.
As Xenopus follows human nomenclature, XB kept the 'like' designation,  so new name is H2A.X variant histone-like, and new symbol for ''Xenopus'' gene is ''h2axl''.
08.23.2019


Human symbol has changed for gene page ID: 855943 From h2afxl to h2aX
Although it has ping-ponged back and forth (the 2019 amnd 2022 changes reversed here), '''DO NOT CHANGE''' back to ''h2afx'', as these are the NOT true orthologs of human H2AFX.- CJZ
 
Human symbol has changed for Entrez Gene: 3014. From H2AFX to H2AX
 
Human name has changed for Entrez Gene: 3014. From H2A histone family member X to H2A.X variant histone
 
17JULY2022
 
Human-Like symbol has changed for genepage ID: 855943 From h2axl to H2AX ( the like is gone!)
 
''Xenopus'' gene changed from ''h2axl'' back to ''h2ax''
 
Note: this page had a few typos with dots (.) in in gene symbols. These have been removed.
 
a synteny/phylogenetic anaylsis might be needed to see if this Xenopus gene is the true ortholog of the human H2AX


=Available Reagents=
=Available Reagents=

Revision as of 08:04, 25 February 2025

h2axl

This is the community wiki page for the gene h2axl please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

On 7/3/2019, this gene was changed from h2afx to h2afxl to designate that it is a like gene. As Xenopus follows human nomenclature, XB kept the 'like' designation, so new name is H2A.X variant histone-like, and new symbol for Xenopus gene is h2axl.

Although it has ping-ponged back and forth (the 2019 amnd 2022 changes reversed here), DO NOT CHANGE back to h2afx, as these are the NOT true orthologs of human H2AFX.- CJZ

Available Reagents

Morpholino Oligonucleotides

Morpholinos have been designed for this gene with sequences
TGACGGCTTTTCCTCTGCCCGACAT

which were used in [1]

This sequence is shared by gene hist2h2ab and may, therefore, be cross-reactive.