XB-FEAT-978289

pals1

This is the community wiki page for the gene pals1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

summary for human PALS1 from NCBI

This gene encodes a member of the p55-like subfamily of the membrane-associated guanylate kinase (MAGUK) gene superfamily. The encoded protein participates in the polarization of differentiating cells, has been shown to regulate myelinating Schwann cells (PMID: 20237282), and is one of the components of the Crumbs complex in the retina. Mice which express lower levels of the orthologous protein have retinal degeneration and impaired vision (PMID: 22114289). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]

nomenclature changes

03.17.2021

Human symbol has changed for genepage ID: 978289 From MPP5 to PALS1

Xenopus symbol has changed for genepage ID: 978289 From mpp5 to pals1

Human symbol has changed for Entrez Gene: 64398. From MPP5 to PALS1

Human name has changed for Entrez Gene: 64398. From membrane palmitoylated protein 5 to protein associated with LIN7 1, MAGUK family member

10.20.2021 Human name has changed for Entrez Gene: 64398 ( PALS1). From protein associated with LIN7 1, MAGUK family member to protein associated with LIN7 1, MAGUK p55 family member