XB-FEAT-940592

capn1

This is the community wiki page for the gene unnamed please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

10.10.2018

Human symbol has changed for genepage ID: 940592 From capn1a to CAPN1

Human name has changed for genepage ID: 940592 from: calpain 1, (mu/I) large subunit a to calpain 1

Summary from NCBI

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]