XB-FEAT-961692

ptprr

This is the community wiki page for the gene ptprr please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

05.13.19 Human name has changed for Entrez Gene: 5801. From protein tyrosine phosphatase, receptor type R to protein tyrosine phosphatase receptor type R

Summary from NCBI for human PTPRR

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]