XB-FEAT-963522

aars1

This is the community wiki page for the gene aars1 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

08.23.2019

Human symbol has changed for genepage ID: 963522 From aars to AARS1

Human symbol has changed for Entrez Gene: 16. From AARS to AARS1

Human name has changed for Entrez Gene: 16. From alanyl-tRNA synthetase to alanyl-tRNA synthetase 1

Summary from NCBI

The human alanyl-tRNA synthetase (AARS) belongs to a family of tRNA synthases, of the class II enzymes. Class II tRNA synthases evolved early in evolution and are highly conserved. This is reflected by the fact that 498 of the 968-residue polypeptide human AARS shares 41% identity witht the E.coli protein. tRNA synthases are the enzymes that interpret the RNA code and attach specific aminoacids to the tRNAs that contain the cognate trinucleotide anticodons. They consist of a catalytic domain which interacts with the amino acid acceptor-T psi C helix of the tRNA, and a second domain which interacts with the rest of the tRNA structure. [provided by RefSeq, Jul 2008]