BAPTA-AM

Description

Selective calcium chelator that is the cell-permeable analog of BAPTA (Cat. No. 2786). Blocks hKv1.5, hKV11.1 (hERG) and hKv1.3 channels (Ki values are 1.23, 1.30 and 1.45 μM respectively). Displays antithrombotic activity in vitro.

Structure of BAPTA-AM, photo from Sigma-Aldrich

• • Genes Affected
  • kcnh2
  • kcna5
  • kcna3

Suppliers

• Life Technologies B1205
• Sigma A1076
• Tocris 2787
• Santa Cruz sc-202488

Usage Notes

.4uM in .1x NAM

References

• Leclerc et al., 2003

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