Nicorandil

Description

Nicorandil is a dual-action potassium channel opener that relaxes vascular smooth muscle through membrane hyperpolarization via increased transmembrane potassium conductance and increased intracellular concentration of cyclic GMP.

nicorandil structure, photo from pubchem

Suppliers

• via pubChem
• Merck KgaA

Usage Notes

4.7uM from stock of 100mg/11mL of water + 1 mL of DMSO

References

• Pubchem
• Cheng et al., 2002

>19 Xenbase articles contain a reference to nicorandil according to textpresso

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