Triptolide

From XenWiki
Revision as of 06:26, 16 November 2018 by imported>Xenbase
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to navigation Jump to search

Description

"Triptolide is a diterpene triepoxide purified from the Chinese herb Tripterygium wilfordii hook (TwHF) and is the principal active ingredient in the herb extract. It is a potent immunosuppressant and anti-inflammatory. Triptolide has been shown to inhibit the expression of IL-2 in activated T cells at the level of purine- box/nuclear factor and NF-κB mediated transcription activation". Source: [1]


structure, image from PubChem

Alternative names

  • PG490


Usage Notes

References

> 4 Xenbase articles contain a reference to Triptolide according to textpresso