XB-FEAT-5942375

igkv3-20l6

This is the community wiki page for the gene igkv3-20l6 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

7Sept2022

Name gene name and symbol changed from XB5758397 to igkv3-20l6, immunoglobulin kappa variable 3-20 like 6.

This gene was named following alignment of the X. tropicalis and X. laevis proteins to precalculated orthology groups in the DIOPT program, EggNogg. It aligned to 900+ other proteins from ~68 species (including to other Xenopus tropicalis proteins) which are named in the IGKV family with high confidence.

The human proteins are called igkv3-20– immunoglobulin kappa variable 3-20, and we have provisionally adopted this gene name. As there is some variability in subfamilies, I have provisionally added the 'like' suffix, and as several genes exist, I've given them serial numbers, this gene being 6.

summary for human IGKV3-20 from AGR and NCBI

Involved in antibacterial humoral response and glomerular filtration. Located in extracellular space. Part of monomeric IgA immunoglobulin complex; pentameric IgM immunoglobulin complex; and secretory IgA immunoglobulin complex. [provided by Alliance of Genome Resources, Apr 2022]