XB-FEAT-22065613

sprtn3

This is the community wiki page for the gene sprtn3, please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomeclature changes

05JAN2023

GENE NAME CHANGED FROM provisional ortholog of SprT-like N-terminal domain TO SprT-like N-terminal domain 3

GENE SYMBOL CHANGED FROM XB22065613 [provisional:sprtn] TO sprtn3

both gene name and symbol are (provisional) awaiting HGNC/NCBI Ref Seq approval.

synteny

X. laevis sprtn.S on Chromosome 5.S seems to be the true orthology of human SPRTN, with both being flanked by eglin1 and exoc8.

Human chr 1: RNA5SP80< ... EXOC8< ... SPRTN> ...LOC107985360> ... EGLN1< ...LOC122152336>

X. laevis chr5.S: sf3b5.S< ... exoc8.S< ...tsnax.S< ... egln1.S< .. sprtn.S> ... acta1.S< ... LOC108717893< ...

the 2 other X. tropicalis genes have been given provisional names sprtn2[geneID: 105945677) and sprtn3 [geneID: 105948375]

X. trop chr1: jsprp1> ...amh< ...sf3a2< ... plekhj1> ... dot1l> ... 'sprtn2'> ... ap3d1> ... mob3a> ... mknk2> ... btbd2> ... csnk1g2< ...

X. trop chr9: gng13> ... chtf18< ... rpusd1> ... msin< ... 'sprtn3'< ... LOC#3326> ... LOC#3470 ...