XB-FEAT-5751696

guca1a

This is the community wiki page for the gene guca1a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

01/12/2016 Human name has changed for Entrez Gene: 2978. From guanylate cyclase activator 1A (retina) to guanylate cyclase activator 1A

07.09.2018 Human symbol has changed for genepage ID: 5751696 From guca1al to guca1a

Human name has changed for Entrez Gene: 2978. guanylate cyclase activator 1A like to guanylate cyclase activator 1A

Also known as

COD3; GCAP; GUCA; GCAP1; GUCA1; CORD14; C6orf131

Summary from NCBI

This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]