XB-FEAT-972563

fto

This is the community wiki page for the gene fto please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

Summary from NCBI for human FTO

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes. [provided by RefSeq, Jul 2011]

nomenclature changes

updated change.

Human name has changed for Entrez Gene: 79068. From fat mass and obesity associated . to FTO, alpha-ketoglutarate dependent dioxygenase

05.13.19 Human name has changed for Entrez Gene: 79068. From FTO, alpha-ketoglutarate dependent dioxygenase to FTO alpha-ketoglutarate dependent dioxygenase