XB-FEAT-987710

fbxl21

This is the community wiki page for the gene fbxl21 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

10/30/2018

Human symbol has changed for genepage ID: 987710 From fbxl21 to fbxl21p

Human symbol has changed for Entrez Gene: 26223. From FBXL21 to FBXL21P

Human name has changed for Entrez Gene: 26223. From F-box and leucine rich repeat protein 21 (gene/pseudogene) to F-box and leucine rich repeat protein 21, pseudogene

3/4/2022

removed ‘pseudogene’ from gene name, as only human gene is thought to be non-functional. Other orthologs are functional protein coding genes.

the mis-match between Xenopus and human gene symbopls/names will consistently trigger a gene name change alert in the monthly Entrez Gene report- (ie Human symbol has changed for genepage ID: 987710 From fbxl21 to FBXL21P DO NOT change the Xenopus symbol- this is a good protein coding gene model in the v10 genome assemblies for Xenopus.

summary from NCBI for human FBXL21P gene

This locus represents a transcribed pseudogene that is related to genes encoding members of the F-box family of proteins. [provided by RefSeq, Nov 2017] Annotation information: Annotation category: suggests misassembly

summary from AGR for mouse FBXL21P gene

involved in entrainment of circadian clock by photoperiod and protein ubiquitination. Located in cytosol and nucleus. Part of SCF ubiquitin ligase complex. Is expressed in gonad; metanephros; nervous system; and stomach. Orthologous to human FBXL21P (F-box and leucine rich repeat protein 21, pseudogene). [provided by Alliance of Genome Resources, Nov 2021]