XB-FEAT-961311

palm2akap2

This is the community wiki page for the gene palm2akap2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

10.18.2019

Human symbol has changed for genepage ID: 961311 From akap2 to palm2akap2

nomenclature notes

As discussed in HGNC-55, HGNC, MGI, and other nomenclature groups have agreed to assign the gene symbol PALM2AKAP2 to the merged genes that had been formerly treated as distinct PALM2 and AKAP2 genes. There is ample support for the separate PALM2 (upstream) and AKAP2 (downstream) transcripts/proteins. In addition, transcription spanning the two (currently annotated as readthrough) is common and deeply conserved throughout gnathostomes, and readthrough transcripts are found in mammals, birds, reptiles and bony fishes. The exon connecting the two is also conserved. Ciona intestinalis also has good evidence of a PALM2-AKAP2 transcript, without apparent separate transcription of a downstream AKAP2 transcript.

XenBase has merged GenePages for palm2 (XB-GENEPAGE-6039053) and akap2 (XB-GENEPAGE-961311).

The NCBI GeneIDs for the fused palm2akap2 genes are:

Xenopus tropicalis GeneID: 100533180

Xenopus laevis L homeolog GeneID: 108713386 Xenopus laevis S homeolog GeneID: 108703733