XB-FEAT-6467139

ces2/ces2.1

This is the community wiki page for the gene ces2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature updates

05JUNE 2023

Xenopus gene changed from ces3.1 to ces3.

nomenclature changes

On December 28, 2018, this gene was changed from ces3 to ces3.1. Evidence includes the Ensembl ces3 gene tree as well as partial synteny with human CES3 locus.

18SEPT2023

Xenopus gene symbol and gene name changed from ces3.1, carboxylesterase 3, gene 1 to ces2.1, carboxylesterase 2, gene 1 following phylogenetic analysis, synteny analysis and by applying Xenopus nomenclature rules to this gene expansion on chromosome 4.

the Xenopus genes are duplicates within a single clade, which is most closely relates to the Human CES2 genes, not the CES3 genes as previously thought

Applying Xenopus nomenclature, we have renamed all CES2 orthologs , with X. tropicalis ces2.1-ces2.8, from left to right, and X. laevis' genes ces2.1.L-ces2.5.L from left to right. There are no genes on the X. laevis S subgenome.