XB-FEAT-5810263

tpx2

This is the community wiki page for the gene tpx2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

summary from NCBI for Human gene TPX2

Enables importin-alpha family protein binding activity; molecular adaptor activity; and protein kinase binding activity. Involved in activation of protein kinase activity; microtubule cytoskeleton organization; and negative regulation of microtubule depolymerization. Located in intercellular bridge; nucleoplasm; and spindle. Is active in spindle. [provided by Alliance of Genome Resources, May 2025]

nomenclature changes

undated

At some point in past, ( prior to 12/01/2018) name changed for tpx2 from 'Xenopus kinesin-like protein 2' to 'TPX2, microtubule nucleation factor '

The gene symbol stayed the same.

Note that species names (Xenopus, Drosophila etc) have been removed from nearly all gene names during period 2010-2020.