XB-FEAT-5858610

nlrc4

This is the community wiki page for the gene nlrc4 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

Summary for human NLRC4 from NCBI

This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]