XB-FEAT-981705

tsc2

This is the community wiki page for the gene tsc2 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

06/26/2017 Human name has changed for Entrez Gene: 7249. From tuberous sclerosis 2 to TSC complex subunit 2

summary from NCBI

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]