XB-FEAT-486826

mrtfa

This is the community wiki page for the gene mrtfa please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

Nomenclature changes

06.19.2018

Human symbol has changed for genepage ID: 486826 From mkl1 to mrtfa

Human symbol has changed for Entrez Gene: 57591. From MKL1 to MRTFA

Human name has changed for Entrez Gene: 57591. From megakaryoblastic leukemia (translocation) 1 to myocardin related transcription factor A

Summary from NCBI

The protein encoded by this gene interacts with the transcription factor myocardin, a key regulator of smooth muscle cell differentiation. The encoded protein is predominantly nuclear and may help transduce signals from the cytoskeleton to the nucleus. This gene is involved in a specific translocation event that creates a fusion of this gene and the RNA-binding motif protein-15 gene. This translocation has been associated with acute megakaryocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]