XB-FEAT-970277

cela2a

This is the community wiki page for the gene cela2a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

01/12/2016 Human name has changed for Entrez Gene: 63036. From chymotrypsin-like elastase family, member 2A to chymotrypsin like elastase family member 2A.

05.13.19 Human name has changed for Entrez Gene: 63036. From chymotrypsin like elastase family member 2A to chymotrypsin like elastase 2A

Summary from NCBI for human CELA2A

Elastases form a subfamily of serine proteases that hydrolyze many proteins in addition to elastin. Humans have six elastase genes which encode the structurally similar proteins elastase 1, 2, 2A, 2B, 3A, and 3B. Like most of the human elastases, elastase 2A is secreted from the pancreas as a zymogen. In other species, elastase 2A has been shown to preferentially cleave proteins after leucine, methionine, and phenylalanine residues. [provided by RefSeq, May 2009]