Small Molecules for Xenopus Research

Important small molecule references

• Database of Small Molecules by Feldman and Hogue 2006 at PubChem
• Wnt/Notch by Myers and Krieg 2014
• Ubiquitin-proteasome by Salic and King 2005

Alphabetical List of Small Molecules With Literature References

• 11-cis retinal
• 18alpha-glycyrretinic acid
• 3,3,5-triiodothyronine (T3)
• 5HT (seratonin)
• activin
• AG1296
• AG1879
• AGN193109
• alpha-amanitin
• anandamide
• apelin
• aphidicolin
• AZD1480
• BAPTA-AM
• beta-xyloside
• bumetanide
• calcium ionophore
• CGP54626
• Chelerythrine
• chymostatin
• concanamycin
• cycloheximide
• cyclopamine
• Cytochalasin B
• dexamethosone
• DHT(dihydrotestosterone)
• Ex-527
• forskolin
• fusicoccin
• gentamycin
• GM6001
• heptanol
• herbimycin A
• IBMX
• KT 5720
• lansoprazol
• LiCl
• Mg132
• mHip
• MMP-2 inhibitor II
• nicorandil
• nifedipine
• nocodazole
• NSC-87877
• o-phenanthroline
• olomoucine
• ouabain
• p-MPPI
• phaclofen
• PMA
• PP2
• primaquin
• propythiouracil
• retinoic acid
• RS67333
• RU486
• SB 203580
• sodium nitroprusside
• SP600125
• SU5402
• SU6656
• Suramin
• thyroxine (T4)
• TTNPB
• tunicamycin
• Y27632
• ZM 447439

List of Molecules Affecting Specific Pathways

cAMP

IBMX

JAK/STAT

• AZD1480

JNK

SP600125

PDGF

• AG1296

Retinoic Acid

• AGN193109
• retinoic acid
• TTNPB

Shh

• cyclopamine
• mHip

Wnt

• LiCl

Epigenetics

• Ex-527

Protease Inhibitors

• chymostatin
• GM6001 (MMP inhibitor)
• o-phenanthroline(MMP inhibitor)

Small Molecules by Biological Function

Angiogenesis

• herbimycin A

Autophagy

• LY-294002

Cytoskeletal Inhibitors

• Cytochalasin B

Growth Cone, Filopodia, and other Cytoskeletal projections

• PP2
• SU6656

Metamorphosis

• 3,3,5-triiodothyronine (T3)
• thyroxine (T4)

Small Molecules Studied in Oocytes Found Via Textpresso

• M119
• GBG or GBetaGamma or G Protein Beta Gamma
• LY-294002 inhibits PI3K and autophagy

Textpresso Small Molecules to Research

• importazole inhibits importin