U0126

Description

"U0126-EtOH is a highly selective inhibitor of MEK1/2 with IC50 of 0.07 μM/0.06 μM in cell-free assays, 100-fold higher affinity for ΔN3-S218E/S222D MEK than PD98059."

• -SelleckChem Product Description

U0126 structure, photo from Sigma-Aldrich

Genes Affected

• map2k1

Suppliers

• Tocris
• InvivoGen
• Promega
• Apex
• Cell Signaling Technology
• SelleckChem
• Sigma

Usage Notes

50uM

References

• Pubchem
• Horne et al., 2003

>185 Xenbase articles contain a reference to U0126 according to textpresso

• Back To Small Molecules Home Page