Echinomycin

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Revision as of 11:52, 17 December 2015 by imported>Kevin (Created page with "http://www.xenbase.org/literature/article.do?method=display&articleId=4170 https://pubchem.ncbi.nlm.nih.gov/compound/3197 Echinomycin is a polypeptide quinoxaline antineoplas...")
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http://www.xenbase.org/literature/article.do?method=display&articleId=4170 https://pubchem.ncbi.nlm.nih.gov/compound/3197

Echinomycin is a polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis. (NCI04)

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