Echinomycin

• http://www.xenbase.org/literature/article.do?method=display&articleId=4170
• https://pubchem.ncbi.nlm.nih.gov/compound/3197

Echinomycin is a polypeptide quinoxaline antineoplastic antibiotic isolated from the bacterium Streptomyces echinatus. Echinomycin intercalates into DNA at two locations simultaneously in a sequence-specific fashion, thereby inhibiting DNA replication and RNA synthesis. (NCI04)