GSK3-inhibitor IX (BIO)

Description

BIO is a reversible and ATP-competitive inhibitor of GSK-3α/β (IC₅₀ = 5 nM) that functions as a WNT pathway activator.

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? structure, image from PubChem

Alternative names

• BIO
• 6BIO
• 6-bromoindirubin-3-oxime

References

• NCBI PubChem CID:5287844
• Woolner and Papalopulu, 2012
• Piper et al., 2015

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