Barasertib

Description

Barasertib specifically binds to and inhibits Aurora kinase B, which results in the disruption of spindle checkpoint functions and chromosome alignment and, so, the disruption of chromosome segregation and cytokinesis.

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? structure, image from PubChem

Alternative names

• AZD1152
• UNII-16XC2U7W8N

Suppliers

• Sigma

References

• [https://pubchem.ncbi.nlm.nih.gov/compound/11497983 NCBI PubChem CID:11497983
• Hanley et al., 2017

> 7 Xenbase articles contain a reference to Barasertib or AZD1152 according to textpresso

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