XB-FEAT-22065605

This is the community wiki page for XB22065605 [provisional:sprtn] - please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

gene model notes

05JAN2023

Although annotated as a provisional ortholog of SprT-like N-terminal domain (sprtn) in the v9.1 Xtropicalis genome annotation, this model was not included/supported in the v10 annotation.

synteny

Xlaevis sprtn.S on Chromosome 5.S seems to be the true orthology of human SPRTN, with both being flanked by eglin1 and exoc8.

Human chr 1: RNA5SP80< ... EXOC8< ... SPRTN> ...LOC107985360> ... EGLN1< ...LOC122152336>

Xlaevis chr5.S: sf3b5.S< ... exoc8.S< ...tsnax.S< ... egln1.S< .. sprtn.S> ... acta1.S< ... LOC108717893< ...

the 2 other X. tropicalis genes have been given provisional names sprtn2[geneID: 105945677) and sprtn3 [geneID: 105948375]

Xtrop chr1: jsprp1> ...amh< ...sf3a2< ... plekhj1> ... dot1l> ... 'sprtn2'> ... ap3d1> ... mob3a> ... mknk2> ... btbd2> ... csnk1g2< ...

Xtrop chr9: gng13> ... chtf18< ... rpusd1> ... msin< ... 'sprtn3'< ... LOC#3326> ... LOC#3470 ...