XB-FEAT-22065609

sprtn2

This is the community wiki page for sprtn2 - please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

nomenclature changes

05JAN2023 gene name changed from provisional ortholog of SprT-like N-terminal domain to SprT-like N-terminal domain like gene 2 (provisional)

gene symbol changed from XB22065609 [provisional:sprtn] to sprtnl2.

both gene name and symbol are (provisional) awaiting HGNC/NCBI Ref Seq approval.

synteny

X. laevis sprtn.S on Chromosome 5.S seems to be the true orthology of human SPRTN, with both being flanked by eglin1 and exoc8.

Human chr 1: RNA5SP80< ... EXOC8< ... SPRTN> ...LOC107985360> ... EGLN1< ...LOC122152336>

X. laevis chr5.S: sf3b5.S< ... exoc8.S< ...tsnax.S< ... egln1.S< .. sprtn.S> ... acta1.S< ... LOC108717893< ...

the 2 other X. tropicalis genes have been given provisional names sprtn2[geneID: 105945677) and sprtn3 [geneID: 105948375]

X. trop chr1: jsprp1> ...amh< ...sf3a2< ... plekhj1> ... dot1l> ... 'sprtnl2'> ... ap3d1> ... mob3a> ... mknk2> ... btbd2> ... csnk1g2< ...

X. trop chr9: gng13> ... chtf18< ... rpusd1> ... msin< ... 'sprtnl3'< ... LOC#3326> ... LOC#3470 ...