XB-FEAT-5900543

or6b1l.5

This is the community wiki page for the gene or6b1l.5 please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

nomenclature changes

3/10/2022

changed gene name and symbol from XB5900543 to olfactory receptor 6B1-like gene 5, or6b1l.5"

gene annotation notes

11January23

The two olfactory receptor genes have been merged into a single model: geneid:108705148 and uid:108705148 (associated with KV467247:OCT56824) which was not currently not placed on the v10 assembly but was formerly placed at NW_016694869.1:453477..454681 as XM_018241948.1:XP_018097437.1.

In the current v10 X laevis assembly, the best placement for XM_018241948.1:XP_018097437.1 (or KV467247:OCT56824) is at NC_054373.1:182543600..182544580 which is where we have NM_001088267:NP_001081736 (uid:398023). Thus, the unplaced uid:108705148 was merged into uid:398023.

This makes sense since uid:108705148 and uid:398023 were both formerly named XB5900543 before being updated in our db to or6b1l.5.L and or6b1l.5.S, respectively. Plus, uid:398023 resides in a cluster of ORs between the arrb1 and slco2b1 genes just as in Xtropicalis or6b1l.5 (uid: 100486700, XB-GENE-5900544, XM_002941568:XP_002941614, also formerly named XB5900543).

We removed uid:108705148 from XB-GENE-5900545 (or6b1l.5.S) as this Entrez geneID has now been deprecated.

summary for human Olfactory receptors genes from NCBI

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

[Some] olfactory receptor gene[s] are segregating pseudogenes, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015, edit by Xb to make text more general].