XB-FEAT-5900919

kdm7a

This is the community wiki page for the gene kdm7a please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase.

summary of gene function

Post-translational histone modifications are among the most common epigenetic modifications that orchestrate gene expression, playing a pivotal role during embryonic development and in various pathological conditions. Among histone lysine demethylases, KDM7A, also known as KIAA1718 or JHDM1D, catalyzes the demethylation of H3K9me1/2 and H3K27me1/2, leading to transcriptional regulation. Previous data suggest that KDM7A plays a central role in several biological processes, including cell proliferation, commitment, differentiation, apoptosis, and maintenance. Source: PMID