XB-FEAT-29078026
chst1l
protein > homology group> nomenclature notes
12.04.2023
protein: carbohydrate sulfotransferase 1 [Xenopus laevis]
NCBI Reference Sequence: XP_018107451.1
>XP_018107451.1 carbohydrate sulfotransferase 1 [Xenopus laevis] MECSWKAVVLLVFASLGIQYTAIKSLRTAFKSPCQVMGGESRCFQRDLRDNASRLLCEDLGQVNRKHIIL LATTRSGSSFLGQIFNQNPDIFYLYEPLYHVQRAFTNSSTRMQKQIDRRSLLGAYRDLLHNLYNCDFYFL ENYLRPAPKDHETTSFFRRGASNALCLPPVCEQLHPIEEHLCSKKCRTVNLTLVSKSCHQYKHMAIKTVR IPEINDIRTLVEDPRLNLKVIHLVRDPRGILASRINTFTDLYRAWKIWNSSGRKPHHIDLSQITTTCTDL SNSVETGFSRPTWLKGKYMLVRYEDLARDPIRKAKEMYEFVGLGWKDNVQKWIEQNTNGNGVPLGNFKFT TSRNAAETAENWRLHLCLDVVLALQNMCNVTLSLLGYQAVHSAPQLKNLSHTLVEPRIFLPFT
This protein, when entered on the EggNogg Tool for homology /orthologous group, hits chst1/CHST1 in over 100 species/136 proteins ( as of 04.dec.2023) confirming its identity. However, there is already a gene called chst1 in Xenopus, and synteny does not support this 2nd loci as being a true orthodox of human CHST1.
Although called chst16 in Yasuoka 2023 [Front Cell Dev Biol 2023 Jan 01;11:957805. doi: 10.3389/fcell.2023.957805.], this is name is not used anywhere else [on NCBI Xenbase or at EBI] for this loci, and is not approved by the VGNC. Given its high similarity to chst1, we are provisionally calling it chst1l, carbohydrate sulfotransferase 1 like, and putting chst16 as a synonym.