XB-FEAT-22065605

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This is the community wiki page for XB22065605 - please feel free to add any information that is relevant to this gene that is not already captured elsewhere in Xenbase

gene model notes

05JAN2023

Although annotated as a provisional ortholog of SprT-like N-terminal domain (sprtn) in the v9.1 Xtropicalis genome annotation, this model was not included/supported in the v10 annotation.

synteny

X. laevis sprtn.S on Chromosome 5.S seems to be the true orthology of human SPRTN, with both being flanked by eglin1 and exoc8.

Human chr 1: RNA5SP80< ... EXOC8< ... SPRTN> ...LOC107985360> ... EGLN1< ...LOC122152336>

X. laevis chr5.S: sf3b5.S< ... exoc8.S< ...tsnax.S< ... egln1.S< .. sprtn.S> ... acta1.S< ... LOC108717893< ...


the 2 other X. tropicalis genes have been given provisional names sprtn2[geneID: 105945677) and sprtn3 [geneID: 105948375]

X. trop chr1: jsprp1> ...amh< ...sf3a2< ... plekhj1> ... dot1l> ... 'sprtn2'> ... ap3d1> ... mob3a> ... mknk2> ... btbd2> ... csnk1g2< ...

X. trop chr9: gng13> ... chtf18< ... rpusd1> ... msin< ... 'sprtn3'< ... LOC#3326> ... LOC#3470 ...

nomenclature change

19AUG2024

gene symbol changed from XB22065605 [provisional:sprtn] to XB22065605, removing the provisional tags

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