XB-FEAT-29081422

tspan4

This is the Xenbase wiki of the Xenopus tspan4 genes. Feel free to record here any relevant information about these genes that is not recorded elsewhere on Xenbase.

nomenclature updates

18NOV2024 Xenopus gene symbol was changed from LOC100492951 to tspan4

summary for human TSPAN4 from NCBI

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein and is similar in sequence to its family member CD53 antigen. It is known to complex with integrins and other transmembrane 4 superfamily proteins. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]